This systematic review was performed to identify the role of photobiomodulation therapy on experimental muscle injury models\nlinked to induce oxidative stress. EMBASE, PubMed, and CINAHL were searched for studies published from January 2006 to\nJanuary 2016 in the areas of laser and oxidative stress. Any animal model using photobiomodulation therapy to modulate\noxidative stress was included in analysis. Eight studies were selected from 68 original articles targeted on laser irradiation and\noxidative stress. Articles were critically assessed by two independent raters with a structured tool for rating the research quality.\nAlthough the small number of studies limits conclusions, the current literature indicates that photobiomodulation therapy can\nbe an effective short-term approach to reduce oxidative stress markers (e.g., thiobarbituric acid-reactive) and to increase\nantioxidant substances (e.g., catalase, glutathione peroxidase, and superoxide dismutase). However, there is a nonuniformity in\nthe terminology used to describe the parameters and dose for low-level laser treatment.
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